Calcium-sensing receptor genotype and response to cinacalcet in patients undergoing hemodialysis

SM Moe, L Wetherill, BS Decker, D Lai… - Clinical Journal of the …, 2017 - journals.lww.com
Results There were modest associations of CASR SNPs with increased baseline serum
parathyroid hormone and bone alkaline phosphatase primarily with the minor allele in the
EA group (all P≤ 0.03), but not in the AfAn sample. In contrast, there was a modest
association of decreased baseline serum calcium and FGF23 with CASR SNPs (P= 0.04)
primarily with the minor allele in the AfAn but not in the EA sample. The minor allele of two
SNPs was associated with decreased percent reduction in parathyroid hormone from …
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